Calcium, Reactive Oxygen Species, and Synaptic Plasticity.
نویسندگان
چکیده
In this review article, we address how activity-dependent Ca(2+)signaling is crucial for hippocampal synaptic/structural plasticity and discuss how changes in neuronal oxidative state affect Ca(2+)signaling and synaptic plasticity. We also analyze current evidence indicating that oxidative stress and abnormal Ca(2+)signaling contribute to age-related synaptic plasticity deterioration.
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ورودعنوان ژورنال:
- Physiology
دوره 31 3 شماره
صفحات -
تاریخ انتشار 2016